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Intracellular nucleic acid sensors and autoimmunity.

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Initially, it was thought that TLR9 is located in the ER in unstimulated cells and is recruited to the endolysosomal compartment only after uptake of TLR9 agonist Latz et al.

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It has die munddusche piss hypothesized that the sensing of naked ssRNA and DNA, which is not associated with pathogen-derived material including non-nucleic acid PAMP, doesn't allow for the discrimination between pathogen-associated vs.

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Bb contains a complex bacterial genome Fraser et al.

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Different patterns of expression and of IL modulation of inflammatory mediators from macrophages of Lyme disease-resistant and -susceptible mice.

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Burden and viability of Borrelia burgdorferi in skin and joints of patients with erythema migrans or lyme arthritis.

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